‘Magic Mushroom’ Company Goes Mainstream, Jumps 71% Post-IPO

Last Friday, U.K.-based Compass Pathways (NASDAQ: CMPS) became the first psychedelic medicine company to go public on a major U.S. exchange. The drugmaker’s shares promptly rose by an eye-catching 70.5% during their first day of trading on the Nasdaq stock exchange…

Compass’ upward momentum, following this historic public debut, appears set to continue today, with the drugmaker’s shares up by 10.8% in pre-market action Monday morning. Compass’ market cap has thus swelled to over $1.1 billion, making it the most valuable psychedelic medicine company in the world.

Compass’ IPO has gotten off to a blistering start thanks to interest from top-notch investors like billionaire and PayPal co-founder Peter Thiel. The core reason is that the company’s lead experimental therapy for treatment-resistant depression (TRD) — known as COMP360 and based on the prodrug compound psilocybin found in over 200 species of magic mushrooms — could be a blockbuster product.

COMP360 is presently in a phase 2 dose-ranging study. Preliminary results from this critical trial may be ready for public consumption as soon as May 2021, according to clinicaltrials.gov. If this phase 2 trial is successful, Compass could have a pivotal phase 3 trial under way by 2022. Early-bird investors are thus looking at a three- to four-year wait for the company to possibly reach the commercial stage of its lifecycle.

Is Compass worth the risk? There are a lot of moving parts to this story. Apart from the inherent risk associated with a mid-stage psych med, therapies derived from psilocybin are surely going to receive a ton of scrutiny from regulators.

Psilocybin, after all, is currently a…

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